Psmb8 (NM_010724) Mouse Recombinant Protein

• Background:

  The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the inflammatory response pathway. Required for adipocyte differentiation (PubMed:21881205, PubMed:22341445, PubMed:8066463) . May be involved in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Lmp-7; Lmp7

• Gene ID:

  16913

• UniProt:

  P28063

• Accession Number mRNA:

  NM_010724

• Chromosomal Location:

  17 17.98 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  30.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Psmb8

• Species:

  Mouse

• Protein ID:

  NP_034854

• Overview:

  Purified recombinant protein of Mouse proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16913

• Uniprot URL:

  https://www.uniprot.org/uniprot/P28063

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010724

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034854