M6pr (NM_010749) Mouse Recombinant Protein

• Background:

  Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  CD-MPR; Mpr46

• Gene ID:

  17113

• UniProt:

  P24668, Q3UKQ5

• Accession Number mRNA:

  NM_010749

• Chromosomal Location:

  6 57.52 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  31.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  M6pr

• Species:

  Mouse

• Protein ID:

  NP_034879

• Overview:

  Purified recombinant protein of Mouse mannose-6-phosphate receptor, cation dependent (M6pr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/17113

• Uniprot URL:

  https://www.uniprot.org/uniprot/P24668

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010749

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034879