Mapre3 (NM_133350) Mouse Recombinant Protein

• Background:

  Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (By similarity) . May play a role in cell migration (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AI790651; EB2; EB3; EBF3; RP3

• Gene ID:

  100732

• UniProt:

  Q6PER3, Q2UZW7

• Accession Number mRNA:

  NM_133350

• Chromosomal Location:

  5 B1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Mapre3

• Species:

  Mouse

• Protein ID:

  NP_579928

• Overview:

  Purified recombinant protein of Mouse microtubule-associated protein, RP/EB family, member 3 (Mapre3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/100732

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6PER3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_133350

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_579928