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Usf1 (BC049784) Mouse Recombinant Protein

CAT: 0882-PM47517M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM47517M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein encoded by this gene is a member of the basic-Helix-Hoop-Helix-Leucine zipper (bHLH-LZ) family and encodes a protein that can act as a transcription factor. Studies indicate that the basic region interacts with DNA at E-Box motifs, while the helix-loop-helix and leucine zipper domains are involved in dimerization with different partners. This protein is involved in a wide array of biological pathways, including cell cycle regulation, immune response, and responses to ultraviolet radiation. Mice lacking most of the coding exons of this gene often lacked both whiskers and nasal fur, and were prone to epileptic seizures, while mice lacking both this gene and another family member, Usf2, displayed embryonic lethality (PMID:9520440) . Mutations in the human ortholog of this gene have been associated with Familial Combined Hyperlipidemia (FCHL) in humans. Pseudogenes of this gene are found on chromosome 11 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Overview
Purified recombinant protein of Mouse upstream transcription factor 1 (cDNA clone MGC:59374 IMAGE:6506829), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
BHLHb11
Gene ID
22278
UniProt
Q61069
Accession Number mRNA
BC049784
Chromosomal Location
1 79.4 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
70.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Usf1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22278
Uniprot URL
https://www.uniprot.org/uniprot/Q61069
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC049784

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