Pex19 (NM_023041) Mouse Recombinant Protein

• Background:

  Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Pxf

• Gene ID:

  19298

• UniProt:

  Q8VCI5

• Accession Number mRNA:

  NM_023041

• Chromosomal Location:

  1 79.54 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  32.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Pex19

• Species:

  Mouse

• Protein ID:

  NP_075528

• Overview:

  Purified recombinant protein of Mouse peroxisomal biogenesis factor 19 (Pex19), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/19298

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8VCI5

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023041

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075528