Aspa (NM_023113) Mouse Recombinant Protein

• Background:

  This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease) . In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease. [provided by RefSeq, Dec 2012]

• Synonyms:

  Acy; Acy-; Acy-2; Acy2; nu; nur7

• Gene ID:

  11484

• UniProt:

  Q8R3P0

• Accession Number mRNA:

  NM_023113

• Chromosomal Location:

  11 B4

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  35.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Aspa

• Species:

  Mouse

• Protein ID:

  NP_075602

• Overview:

  Purified recombinant protein of Mouse aspartoacylase (Aspa), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11484

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R3P0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_023113

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_075602