Sox2 (NM_011443) Mouse Recombinant Protein

• Background:

  This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in a similar gene in human have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (Sox2ot) . [provided by RefSeq, Sep 2015]

• Synonyms:

  Lc; lcc; Sox; Sox-2; ys; ysb

• Gene ID:

  20674

• UniProt:

  P48432, Q60I23

• Accession Number mRNA:

  NM_011443

• Chromosomal Location:

  3 16.93 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  34.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Sox2

• Species:

  Mouse

• Protein ID:

  NP_035573

• Overview:

  Purified recombinant protein of Mouse SRY (sex determining region Y) -box 2 (Sox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20674

• Uniprot URL:

  https://www.uniprot.org/uniprot/P48432

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011443

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035573