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Psmc5 (BC030840) Mouse Recombinant Protein

CAT: 0882-PM47050M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM47050M5Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse protease (prosome, macropain) 26S subunit, ATPase 5 (cDNA clone MGC:31044 IMAGE:3994523), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
MSUG1
Gene ID
19184
UniProt
P62196
Accession Number mRNA
BC030840
Chromosomal Location
11 E1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
38.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Psmc5
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19184
Uniprot URL
https://www.uniprot.org/uniprot/P62196
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC030840

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