Atp6v0d1 (NM_013477) Mouse Recombinant Protein

• Background:

  Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity) . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe (2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Ac39; AI267038; Atp6d; P39; VATX; Vma6

• Gene ID:

  11972

• UniProt:

  P51863

• Accession Number mRNA:

  NM_013477

• Chromosomal Location:

  8 D3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  40.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Atp6v0d1

• Species:

  Mouse

• Protein ID:

  NP_038505

• Overview:

  Purified recombinant protein of Mouse ATPase, H+ transporting, lysosomal V0 subunit D1 (Atp6v0d1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11972

• Uniprot URL:

  https://www.uniprot.org/uniprot/P51863

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013477

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_038505