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Pnpla2 (BC019188) Mouse Recombinant Protein

CAT: 0882-PM46417M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46417M5Size:20 µg
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Background
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674) . Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse patatin-like phospholipase domain containing 2 (cDNA clone MGC:29206 IMAGE:5027544), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
TTS-2.2, Atgl
Gene ID
66853
UniProt
Q8BJ56
Accession Number mRNA
BC019188
Chromosomal Location
7 F5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
75.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Pnpla2
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66853
Uniprot URL
https://www.uniprot.org/uniprot/Q8BJ56
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC019188

UniProtKB · Q8BJ56

Patatin-like phospholipase domain-containing protein 2

PLPL2_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8BJ56
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Pnpla2
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
3.1.1.3
Processing
—
Secondary accessions
O89080, Q05BJ0, Q3UD97, Q643S0, Q6P234, Q9D1Q9, Q9DCF6
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmLipid dropletMembrane

PTM

GlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Hydrolase

Biological process

Lipid degradationLipid metabolism

Technical term

Reference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

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