Tulp3 (NM_011657) Mouse Recombinant Protein

• Background:

  Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2310022L06Rik; AI316887

• Gene ID:

  22158

• UniProt:

  O88413

• Accession Number mRNA:

  NM_011657

• Chromosomal Location:

  6 62.96 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  51.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Tulp3

• Species:

  Mouse

• Protein ID:

  NP_035787

• Overview:

  Purified recombinant protein of Mouse tubby-like protein 3 (Tulp3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/22158

• Uniprot URL:

  https://www.uniprot.org/uniprot/O88413

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011657

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035787