Ctsc (NM_009982) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the dipeptidyl peptidase 1 light, heavy, and exclusion domain chains, which together comprise one subunit of the homotetrameric enzyme. This enzyme has amino dipeptidase activity and may play a role in the activation of granzymes during inflammation. Homozygous knockout mice for this gene exhibit impaired granzyme activation and enhanced survival in a sepsis model. [provided by RefSeq, Aug 2015]

• Synonyms:

  AI047818; CatC; D; DP; DPP1; DPPI

• Gene ID:

  13032

• UniProt:

  P97821, Q3UBY5, Q8BQL3

• Accession Number mRNA:

  NM_009982

• Chromosomal Location:

  7 D3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  52.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ctsc

• Species:

  Mouse

• Protein ID:

  NP_034112

• Overview:

  Purified recombinant protein of Mouse cathepsin C (Ctsc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/13032

• Uniprot URL:

  https://www.uniprot.org/uniprot/P97821

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009982

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034112