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Gck (BC011139) Mouse Recombinant Protein

CAT: 0882-PM46204M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46204M5Size:20 µg
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Background
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse glucokinase (cDNA clone MGC:18414 IMAGE:4195943), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
GLK, Gk, HK4, HKIV, HXKP, MODY2, NIDDM
Gene ID
103988
UniProt
P52792
Accession Number mRNA
BC011139
Chromosomal Location
11 3.88 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
51.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Gck
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/103988
Uniprot URL
https://www.uniprot.org/uniprot/P52792
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC011139

UniProtKB · P52792

Hexokinase-4

HXK4_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P52792
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Gck
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
HK4
EC number
2.7.1.1
Processing
—
Secondary accessions
P52791
Protein keywords

Molecular function

Allosteric enzymeKinaseTransferase

Coding sequence diversity

Alternative promoter usageAlternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmMitochondrionNucleus

Biological process

Glycolysis

Technical term

Reference proteome

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