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Cacnb1 (BC077713) Mouse Recombinant Protein

CAT: 0882-PM46168M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM46168M5Size:20 µg
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Background
Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity) . Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse calcium channel, voltage-dependent, beta 1 subunit (cDNA clone MGC:69994 IMAGE:30288369), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
CAB1; Cchb1; Cchlb1
Gene ID
12295
UniProt
Q8R3Z5
Accession Number mRNA
BC077713
Chromosomal Location
11 61.5 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
63.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cacnb1
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12295
Uniprot URL
https://www.uniprot.org/uniprot/Q8R3Z5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC077713

UniProtKB · Q8R3Z5

Voltage-dependent L-type calcium channel subunit beta-1

CACB1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q8R3Z5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cacnb1
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
CAB1
EC number
—
Processing
—
Secondary accessions
A2A544, O88517, Q7TPF2, Q8R3Z6, Q9EPT9
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Ligand

Calcium

Molecular function

Calcium channelIon channelVoltage-gated channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneMembrane

PTM

Phosphoprotein

Domain

SH3 domain

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