Pi4k2a (BC022127) Mouse Recombinant Protein

• Background:

  Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MGC37783, Pi4k2

• Gene ID:

  84095

• UniProt:

  Q2TBE6

• Accession Number mRNA:

  BC022127

• Chromosomal Location:

  19 35.74 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  71.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Pi4k2a

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/84095

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q2TBE6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC022127