Rftn2 (NM_028713) Mouse Recombinant Protein

• Background:

  Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195) . May regulate B-cell antigen receptor-mediated signaling.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2700010E02Rik; 3222401M22Rik

• Gene ID:

  74013

• UniProt:

  Q8CHX7

• Accession Number mRNA:

  NM_028713

• Chromosomal Location:

  1 C1.2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  55 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Rftn2

• Species:

  Mouse

• Protein ID:

  NP_082989

• Overview:

  Purified recombinant protein of Mouse raftlin family member 2 (Rftn2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/74013

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8CHX7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_028713

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_082989