Impdh1 (NM_011829) Mouse Recombinant Protein

• Background:

  Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  B930086D20Rik; IMPDH-I

• Gene ID:

  23917

• UniProt:

  P50096

• Accession Number mRNA:

  NM_011829

• Chromosomal Location:

  6 A3.3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  55.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Impdh1

• Species:

  Mouse

• Protein ID:

  NP_035959

• Overview:

  Purified recombinant protein of Mouse inosine monophosphate dehydrogenase 1 (Impdh1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23917

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50096

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011829

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035959