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Abcd4 (BC050102) Mouse Recombinant Protein

CAT: 0882-PM45882M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM45882M5Size:20 µg
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Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that the human protein may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Mouse ATP-binding cassette, sub-family D (ALD), member 4 (cDNA clone MGC:60642 IMAGE:30012556), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
P69r, P70R
Gene ID
19300
UniProt
O89016
Accession Number mRNA
BC050102
Chromosomal Location
12 39.3 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
58.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Abcd4
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19300
Uniprot URL
https://www.uniprot.org/uniprot/O89016
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC050102

UniProtKB · O89016

Lysosomal cobalamin transporter ABCD4

ABCD4_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
O89016
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Abcd4
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
7.6.2.8
Processing
—
Secondary accessions
E9QKU3
Protein keywords

Ligand

ATP-bindingNucleotide-binding

Cellular component

Endoplasmic reticulumLysosomeMembrane

Technical term

Reference proteome

Molecular function

Translocase

Domain

TransmembraneTransmembrane helix

Biological process

Transport

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