Shoc2 (BC026364) Mouse Recombinant Protein

• Background:

  Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Sur8, Sur-8

• Gene ID:

  56392

• UniProt:

  O88520

• Accession Number mRNA:

  BC026364

• Chromosomal Location:

  19 D2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  58.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Shoc2

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse soc-2 (suppressor of clear) homolog (C. elegans) (cDNA clone MGC:31051 IMAGE:4014650), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/56392

• Uniprot URL:

  https://www.uniprot.org/uniprot/O88520

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC026364