Cry2 (BC054794) Mouse Recombinant Protein

• Background:

  This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. [provided by RefSeq, Feb 2014]

• Synonyms:

  AV006279; D130054K12Rik

• Gene ID:

  12953

• UniProt:

  Q9R194

• Accession Number mRNA:

  BC054794

• Chromosomal Location:

  2 E1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  66.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cry2

• Species:

  Mouse

• Overview:

  Purified recombinant protein of Mouse cryptochrome 2 (photolyase-like) (cDNA clone MGC:65642 IMAGE:6834104), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12953

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9R194

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/BC054794