Cc2d1a (NM_145970) Mouse Recombinant Protein

• Background:

  Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  BC016188; Freud-1; Tape

• Gene ID:

  212139

• UniProt:

  Q8K1A6

• Accession Number mRNA:

  NM_145970

• Chromosomal Location:

  8 C2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  103.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cc2d1a

• Species:

  Mouse

• Protein ID:

  NP_666082

• Overview:

  Purified recombinant protein of Mouse coiled-coil and C2 domain containing 1A (Cc2d1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/212139

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8K1A6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_145970

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_666082