Nr4a1 (NM_010444) Mouse Recombinant Protein

• Background:

  Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity) . Plays a role in the vascular response to injury (PubMed:22427340) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Gfrp; GFRP1; Hbr-1; Hbr1; Hmr; N10; NGFI-B; NGFIB; NP10; nur77; TIS1; TR3

• Gene ID:

  15370

• UniProt:

  P12813, Q545Q1

• Accession Number mRNA:

  NM_010444

• Chromosomal Location:

  15 F1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  64.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Nr4a1

• Species:

  Mouse

• Protein ID:

  NP_034574

• Overview:

  Purified recombinant protein of Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/15370

• Uniprot URL:

  https://www.uniprot.org/uniprot/P12813

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010444

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034574