Gga1 (NM_145929) Mouse Recombinant Protein

• Background:

  Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes (PubMed:25405894) . Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface (By similarity) . Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane (PubMed:25405894) . Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  4930406E12Rik; AU016030; AW209092

• Gene ID:

  106039

• UniProt:

  Q8R0H9

• Accession Number mRNA:

  NM_145929

• Chromosomal Location:

  15 E1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  70 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Gga1

• Species:

  Mouse

• Protein ID:

  NP_666041

• Overview:

  Purified recombinant protein of Mouse golgi associated, gamma adaptin ear containing, ARF binding protein 1 (Gga1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/106039

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R0H9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_145929

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_666041