Flrt2 (NM_201518) Mouse Recombinant Protein

• Background:

  Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:21350012, PubMed:25728924 PubMed:25374360) . May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D (PubMed:21673655) . Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members (PubMed:21673655, PubMed:25728924) . Plays a role in fibroblast growth factor-mediated signaling cascades (PubMed:16872596) . Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis (PubMed:21350012) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  KIAA0405

• Gene ID:

  399558

• UniProt:

  Q8BLU0

• Accession Number mRNA:

  NM_201518

• Chromosomal Location:

  12 E

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  74.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Flrt2

• Species:

  Mouse

• Protein ID:

  NP_958926

• Overview:

  Purified recombinant protein of Mouse fibronectin leucine rich transmembrane protein 2 (Flrt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/399558

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8BLU0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_201518

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_958926