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Cast (BC010603) Mouse Recombinant Protein

CAT: 0882-PM45313M5Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM45313M5Size:20 µg
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Background
This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each other. Some isoforms may be tissue-specific. Two different pseudogenes of this gene are found on chromosome 19. [provided by RefSeq, Jul 2014]
Overview
Purified recombinant protein of Mouse calpastatin (cDNA clone MGC:12116 IMAGE:3710078), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID
12380
UniProt
P51125
Accession Number mRNA
BC010603
Chromosomal Location
13 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
73 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cast
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12380
Uniprot URL
https://www.uniprot.org/uniprot/P51125
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC010603

UniProtKB · P51125

Calpastatin

ICAL_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P51125
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cast
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1
Protein keywords

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

Protease inhibitorThiol protease inhibitor

Technical term

Reference proteome

Domain

Repeat

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