Sec23a (NM_009147) Mouse Recombinant Protein

• Background:

  Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) . The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity) . Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane (PubMed:27354378) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Msec23; Sec23r

• Gene ID:

  20334

• UniProt:

  Q01405, Q8C1E4

• Accession Number mRNA:

  NM_009147

• Chromosomal Location:

  12 C1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  86.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Sec23a

• Species:

  Mouse

• Protein ID:

  NP_033173

• Overview:

  Purified recombinant protein of Mouse SEC23 homolog A, COPII coat complex component (Sec23a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20334

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q01405

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009147

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033173