Atxn1 (NM_009124) Mouse Recombinant Protein

• Background:

  Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity) . May be involved in RNA metabolism (By similarity) . In concert with CIC and ATXN1L, involved in brain development (PubMed:28288114) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2900016G23Rik; Atx1; C85907; ENSMUSG00000074917; Gm10786; Sca1

• Gene ID:

  20238

• UniProt:

  P54254

• Accession Number mRNA:

  NM_009124

• Chromosomal Location:

  13 21.98 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  83.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Atxn1

• Species:

  Mouse

• Protein ID:

  NP_033150

• Overview:

  Purified recombinant protein of Mouse ataxin 1 (Atxn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20238

• Uniprot URL:

  https://www.uniprot.org/uniprot/P54254

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_009124

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_033150