Bend3 (NM_199028) Mouse Recombinant Protein

• Background:

  Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (By similarity) . Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites (PubMed:25457167) . Stimulates the ERCC6L translocase and ATPase activities (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MKIAA1553

• Gene ID:

  331623

• UniProt:

  Q6PAL0

• Accession Number mRNA:

  NM_199028

• Chromosomal Location:

  10 B2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  94.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Bend3

• Species:

  Mouse

• Protein ID:

  NP_950193

• Overview:

  Purified recombinant protein of Mouse BEN domain containing 3 (Bend3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/331623

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6PAL0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_199028

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_950193