Nedd9 (NM_001111324) Mouse Recombinant Protein

• Background:

  Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cas-L; CasL; HEF1; MEF1; Nedd-9; p105

• Gene ID:

  18003

• UniProt:

  O35177

• Accession Number mRNA:

  NM_001111324

• Chromosomal Location:

  13 A3.3- A4

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  93.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Nedd9

• Species:

  Mouse

• Protein ID:

  NP_001104794

• Overview:

  Purified recombinant protein of Mouse neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/18003

• Uniprot URL:

  https://www.uniprot.org/uniprot/O35177

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001111324

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001104794