Vps39 (NM_178851) Mouse Recombinant Protein

• Background:

  May play a role in clustering and fusion of late endosomes and lysosomes (By similarity) . Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  A230065P22Rik; AW743070; mVam6; Vam6; Vam6P

• Gene ID:

  269338

• UniProt:

  Q8R5L3, Q5KU38

• Accession Number mRNA:

  NM_178851

• Chromosomal Location:

  2 E5

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  101.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Vps39

• Species:

  Mouse

• Protein ID:

  NP_849182

• Overview:

  Purified recombinant protein of Mouse VPS39 HOPS complex subunit (Vps39), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/269338

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R5L3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_178851

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_849182