Ints5 (NM_176843) Mouse Recombinant Protein

• Background:

  Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1110055N21Rik; mKIAA1698

• Gene ID:

  109077

• UniProt:

  Q8CHT3

• Accession Number mRNA:

  NM_176843

• Chromosomal Location:

  19 A

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  108.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ints5

• Species:

  Mouse

• Protein ID:

  NP_789813

• Overview:

  Purified recombinant protein of Mouse integrator complex subunit 5 (Ints5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/109077

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8CHT3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_176843

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_789813