Pdgfra (NM_001083316) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the receptor tyrosine kinase family of proteins. Binding of platelet-derived growth factor protein ligands to this receptor triggers receptor dimerization and autophosphorylation, resulting in the activation of several downstream signaling pathways. Signaling through the encoded receptor plays a role in gastrulation and the development of nearly all organ systems. Mice lacking a functional copy of this gene reportedly exhibit defects in lung, skeleton, testis and the central nervous system, and die soon after birth. Alternative splicing and intronic polyadenylation of gene transcripts have been implicated in muscle regeneration and fibrosis in adult mice. [provided by RefSeq, Jan 2017]

• Synonyms:

  AI115593; CD140; CD140a; Pdgfr; Pdgfr-2

• Gene ID:

  18595

• UniProt:

  P26618

• Accession Number mRNA:

  NM_001083316

• Chromosomal Location:

  5 39.55 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  123.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Pdgfra

• Species:

  Mouse

• Protein ID:

  NP_001076785

• Overview:

  Purified recombinant protein of Mouse platelet derived growth factor receptor, alpha polypeptide (Pdgfra), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/18595

• Uniprot URL:

  https://www.uniprot.org/uniprot/P26618

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001083316

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001076785