Traf3ip1 (NM_028718) Mouse Recombinant Protein

• Background:

  Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity) . Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268) . Involved in ciliogenesis (PubMed:21945076) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  3930402D05Rik; AU041749; MIP-T3

• Gene ID:

  74019

• UniProt:

  Q149C2

• Accession Number mRNA:

  NM_028718

• Chromosomal Location:

  1 D

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  71 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Traf3ip1

• Species:

  Mouse

• Protein ID:

  NP_082994

• Overview:

  Purified recombinant protein of Mouse TRAF3 interacting protein 1 (Traf3ip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/74019

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q149C2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_028718

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_082994