Cobl (NM_172496) Mouse Recombinant Protein

• Background:

  Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin) . Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  4732460E13; C530045F18Rik; mKIAA0633

• Gene ID:

  12808

• UniProt:

  Q5NBX1

• Accession Number mRNA:

  NM_172496

• Chromosomal Location:

  11 7.3 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  143.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Cobl

• Species:

  Mouse

• Protein ID:

  NP_766084

• Overview:

  Purified recombinant protein of Mouse cordon-bleu WH2 repeat (Cobl), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/12808

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5NBX1

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_172496

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_766084