Gcsam (NM_001159297) Mouse Recombinant Protein

• Background:

  Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Gcet; Gcet2; M17; M17-L

• Gene ID:

  14525

• UniProt:

  Q6RFH4

• Accession Number mRNA:

  NM_001159297

• Chromosomal Location:

  16 B5

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  21 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Gcsam

• Species:

  Mouse

• Protein ID:

  NP_001152769

• Overview:

  Purified recombinant protein of Mouse germinal center associated, signaling and motility (Gcsam), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/14525

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6RFH4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001159297

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001152769