Pik3ap1 (NM_031376) Mouse Recombinant Protein

• Background:

  Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K) -Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1810044J04Rik; BCAP

• Gene ID:

  83490

• UniProt:

  Q9EQ32

• Accession Number mRNA:

  NM_031376

• Chromosomal Location:

  19 C3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  91.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Pik3ap1

• Species:

  Mouse

• Protein ID:

  NP_113553

• Overview:

  Purified recombinant protein of Mouse phosphoinositide-3-kinase adaptor protein 1 (Pik3ap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/83490

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9EQ32

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_031376

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_113553