Ptprr (NM_011217) Mouse Recombinant Protein

• Background:

  Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Isoform gamma may have a role in patterning and cellular proliferation of skeletal elements in the precartilaginous/cartilaginous skeleton.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Gmcp1; mPTP213; PTP-SL; PTPBR7; RPTPRR

• Gene ID:

  19279

• UniProt:

  Q62132, Q5U1U6, Q8CEI8

• Accession Number mRNA:

  NM_011217

• Chromosomal Location:

  10 D2

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  74.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ptprr

• Species:

  Mouse

• Protein ID:

  NP_035347

• Overview:

  Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, R (Ptprr), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/19279

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q62132

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011217

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035347