Ptpre (NM_011212) Mouse Recombinant Protein

• Background:

  Isoform 1 acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through direct dephosphorylation and inactivation of IR in hepatocytes and liver (By similarity) . Plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  PTPe; PTPepsilon; RPTPepsilon

• Gene ID:

  19267

• UniProt:

  P49446

• Accession Number mRNA:

  NM_011212

• Chromosomal Location:

  7 81.27 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  81.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ptpre

• Species:

  Mouse

• Protein ID:

  NP_035342

• Overview:

  Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, E (Ptpre), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/19267

• Uniprot URL:

  https://www.uniprot.org/uniprot/P49446

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011212

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035342