Unc5a (NM_153131) Mouse Recombinant Protein

• Background:

  Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MKIAA1976; Unc5h1

• Gene ID:

  107448

• UniProt:

  Q8K1S4

• Accession Number mRNA:

  NM_153131

• Chromosomal Location:

  13 B1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  99.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Unc5a

• Species:

  Mouse

• Protein ID:

  NP_694771

• Overview:

  Purified recombinant protein of Mouse unc-5 netrin receptor A (Unc5a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/107448

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8K1S4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_153131

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_694771