Necab2 (NM_054095) Mouse Recombinant Protein

• Background:

  May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Efcbp2

• Gene ID:

  117148

• UniProt:

  Q91ZP9

• Accession Number mRNA:

  NM_054095

• Chromosomal Location:

  8 E1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  43.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Necab2

• Species:

  Mouse

• Protein ID:

  NP_473436

• Overview:

  Purified recombinant protein of Mouse N-terminal EF-hand calcium binding protein 2 (Necab2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/117148

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q91ZP9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_054095

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_473436