Papss2 (NM_011864) Mouse Recombinant Protein

• Background:

  Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase) . In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have an important role in skeletogenesis during postnatal growth.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1810018P12Rik; AI159688; Atpsk2; AtpsU2; bm; Sk2

• Gene ID:

  23972

• UniProt:

  O88428

• Accession Number mRNA:

  NM_011864

• Chromosomal Location:

  19 27.46 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  70.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Papss2

• Species:

  Mouse

• Protein ID:

  NP_035994

• Overview:

  Purified recombinant protein of Mouse 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/23972

• Uniprot URL:

  https://www.uniprot.org/uniprot/O88428

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011864

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035994