Sycp3 (NM_011517) Mouse Recombinant Protein

• Background:

  Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:11311943, PubMed:22761579) . Required for centromere pairing during meiosis in male germ cells (PubMed:22761579) . Required for normal meiosis during spermatogenesis and male fertility (PubMed:10678170) . Plays a lesser role in female fertility (PubMed:10678170, PubMed:12004129) . Required for efficient phosphorylation of HORMAD1 and HORMAD2 (PubMed:22346761) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  Cor1; Scp3

• Gene ID:

  20962

• UniProt:

  P70281, A2RSE7

• Accession Number mRNA:

  NM_011517

• Chromosomal Location:

  10 C1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  29.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Sycp3

• Species:

  Mouse

• Protein ID:

  NP_035647

• Overview:

  Purified recombinant protein of Mouse synaptonemal complex protein 3 (Sycp3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20962

• Uniprot URL:

  https://www.uniprot.org/uniprot/P70281

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011517

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_035647