Mc4r (NM_016977) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors, which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As part of the central nervous melanocortin system, the encoded protein is competitively bound by either melanocyte stimulating hormone or agouti-related protein to regulate energy homeostasis. Disruption of this gene promotes hyperphagia and obesity, and is associated with increased cholesterol levels and insulin resistance. [provided by RefSeq, Dec 2012]

• Synonyms:

  Fatb; Mc4-r; Pk; Pkcp

• Gene ID:

  17202

• UniProt:

  P56450

• Accession Number mRNA:

  NM_016977

• Chromosomal Location:

  18 E1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  37 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Mc4r

• Species:

  Mouse

• Protein ID:

  NP_058673

• Overview:

  Purified recombinant protein of Mouse melanocortin 4 receptor (Mc4r), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/17202

• Uniprot URL:

  https://www.uniprot.org/uniprot/P56450

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016977

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_058673