Slurp1 (NM_020519) Mouse Recombinant Protein

• Background:

  Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner (By similarity) . In T cells may be involved in regulation of intracellular Ca (2+) signaling (PubMed:17286989) . Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation (PubMed:23139280, PubMed:25168896) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  1110021N19Rik; AI415082; ARS; ArsB; Slurp-1

• Gene ID:

  57277

• UniProt:

  Q9Z0K7

• Accession Number mRNA:

  NM_020519

• Chromosomal Location:

  15 D3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  12 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Slurp1

• Species:

  Mouse

• Protein ID:

  NP_065265

• Overview:

  Purified recombinant protein of Mouse secreted Ly6/Plaur domain containing 1 (Slurp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/57277

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Z0K7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_020519

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_065265