Plxna1 (NM_008881) Mouse Recombinant Protein

• Background:

  Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2600013D04Rik; mKIAA4053; NOV; PlexA1; Plxn1

• Gene ID:

  18844

• UniProt:

  P70206

• Accession Number mRNA:

  NM_008881

• Chromosomal Location:

  6 D1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  211.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Plxna1

• Species:

  Mouse

• Protein ID:

  NP_032907

• Overview:

  Purified recombinant protein of Mouse plexin A1 (Plxna1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/18844

• Uniprot URL:

  https://www.uniprot.org/uniprot/P70206

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008881

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032907