Esr1 (NM_007956) Mouse Recombinant Protein

• Background:

  This gene encodes an estrogen receptor, a member of the nuclear hormone family of intracellular receptors. The encoded protein, activated by the sex hormone estrogen, is a transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Similar genes in human have been implicated in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

• Synonyms:

  E; ER; ER-; ER-alpha; ERa; ERalpha; ER[; Es; ESR; Estr; Estra; Nr; Nr3a1

• Gene ID:

  13982

• UniProt:

  P19785, E7FJU2

• Accession Number mRNA:

  NM_007956

• Chromosomal Location:

  10 2.03 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  67.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Esr1

• Species:

  Mouse

• Protein ID:

  NP_031982

• Overview:

  Purified recombinant protein of Mouse estrogen receptor 1 (alpha) (Esr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/13982

• Uniprot URL:

  https://www.uniprot.org/uniprot/P19785

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007956

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_031982