Mstn (NM_010834) Mouse Recombinant Protein

• Background:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Homozygous knockout mice for this gene exhibit increased muscle mass and bone density, and reduced adiposity. [provided by RefSeq, Jul 2016]

• Synonyms:

  Cmpt; Gdf8

• Gene ID:

  17700

• UniProt:

  O08689, Q540E2

• Accession Number mRNA:

  NM_010834

• Chromosomal Location:

  1 26.99 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  42.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Mstn

• Species:

  Mouse

• Protein ID:

  NP_034964

• Overview:

  Purified recombinant protein of Mouse myostatin (Mstn), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/17700

• Uniprot URL:

  https://www.uniprot.org/uniprot/O08689

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010834

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034964