MUSK (NM_005592) Human Recombinant Protein

• Background:

  This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009]

• Synonyms:

  CMS9; FADS; MGC126323; MGC126324

• Gene ID:

  4593

• UniProt:

  O15146

• Accession Number mRNA:

  NM_005592

• Chromosomal Location:

  9q31.3

• Expression System:

  HEK293

• Tag:

  C-DDK/His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase, Transmembrane

• Molecular Weight:

  55 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MUSK

• Species:

  Human

• Protein ID:

  NP_005583

• Overview:

  Purified recombinant protein of human muscle, skeletal, receptor tyrosine kinase (MUSK), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4593

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15146

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005592

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005583