MERTK (NM_006343) Human Recombinant Protein

• Background:

  This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) . [provided by RefSeq, Jul 2008]

• Synonyms:

  C-Eyk; c-mer; MER; RP38; Tyro12

• Gene ID:

  10461

• UniProt:

  Q12866

• Accession Number mRNA:

  NM_006343

• Chromosomal Location:

  2q13

• Expression System:

  HEK293

• Tag:

  C-DDK/His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase, Transmembrane

• Molecular Weight:

  55 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MERTK

• Species:

  Human

• Protein ID:

  NP_006334

• Overview:

  Purified recombinant protein of human c-mer proto-oncogene tyrosine kinase (MERTK), with C-terminal DDK/His tag, expressed in human cells, 20 µg

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10461

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q12866

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_006343

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_006334