P2X2 (P2RX2) (NM_170682) Human Recombinant Protein

• Background:

  The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]

• Synonyms:

  DFNA41; P2X2

• Gene ID:

  22953

• UniProt:

  Q9UBL9, Q32MC3

• Accession Number mRNA:

  NM_170682

• Chromosomal Location:

  12q24.33

• Expression System:

  HEK293

• Tag:

  C-Myc/DDK

• Related Pathways:

  Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Field of Research:

  Calcium signaling pathway, Neuroactive ligand-receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Ion Channels: ATP Receptors, Transmembrane

• Molecular Weight:

  51.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  P2RX2

• Species:

  Human

• Protein ID:

  NP_733782

• Overview:

  Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), K81A mutant of transcript variant 1, 20 ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/22953

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UBL9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_170682

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_733782